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Buying Leads | Show Policy, Bulletin of the Chemical Society of Japan, PDF Large-conductance calcium-activated potassium (BK) channels are involved in many fundamental cell functions. Andere Namen. Eur J Med Chem. Calderone V, Fiamingo FL, Amato G, Giorgi I, Livi O, Martelli A, Martinotti E. Eur J Med Chem. Acta Crystallogr Sect E Struct Rep Online. Benzanilide Names Preferred IUPAC name. 2009 Jun 20;65(Pt 7):o1637-8. In particular, a new series of benzanilides, in which the phenyl rings have been widely changed both on the acidic portion and the basic one of the … 245. Antimycobacterial activity of salicylanilide benzenesulfonates. Articles of Benzanilide are included as well. Krátký M, Vinšová J, Rodriguez NG, Stolaříková J. Molecules. Benzanilid kann durch Reaktion von Benzoesäure oder Benzoylchlorid mit Anilin gewonnen werden. VII. NIH II. The absorption and fluorescence spectra of fast violet-B (FVB) and benzanilide (BA) have been analysed in different solvents, pH and beta-cyclodextrin. Benzanilides with spasmolytic activity: chemistry, pharmacology, and SAR. The sheets are stacked along a with disorder by van der Waals interactions. ass: Standard non-polar; Column type: Capillary; CAS no: 93981; Active phase: Polydimethyl siloxanes; Data type: Normal alkane RI; Authors: Zenkevich, I.G. The molecules related by a b-translation are linked together by N–H…O hydrogen bond [N…O 3.112(6), H…O 2.03 Å, N–H…O 157°] to form a chain along b. Synthesis of Benzanilide; Benzanilide (CAS NO. Service | ; Chupalov, A.A., New Possibilities of Chromato Mass Pectrometric Identification of Organic Compounds Using Increments of Gas Chromatographic Retention Indices of Molecular Structural Fragments, Zh. Articles of Benzanilide are included as well. [2], Es kann auch aus Benzophenonoxim durch Umlagerung nach Beckmann mit Phosphorpentachlorid in Diethylether hergestellt werden. Clipboard, Search History, and several other advanced features are temporarily unavailable.  |  Commercially available, it may be prepared by treating benzoic acid with aniline. The optimized structure for trans-benzanilide and cis-benzanilide is non-planar with a tilted shape. On the relationship between the substitution pattern of thiobenzanilides and their antimycobacterial activity. Spectrosc. ), 32(5), 1996, 656-666, In original 656-666. Hagenow J, Hagenow S, Grau K, Khanfar M, Hefke L, Proschak E, Stark H. Drug Des Devel Ther. Khim. All compounds were synthesized in good ... Spectrochim.

Org. Laboratory Manual of Organic Chemistry by Raj K. Bansal, Page No.111. These are organic compounds containing a carboxamido substituent attached to a benzene ring. The crystals are monoclinic, space group C2/c, Z=4, with a=24.34(4), b=5.325(3), c=8.012(8) Å, β=107.2(3)°, Dm=1.32 and Dx=1.321 g cm−3. In this perspective, the development of new and selective BK-openers can be considered as an actual field of research. Journals | MFN tariff:6.5%. 4-Chloro-N-(2,6-dichloro-phen-yl)benzamide.
In a 3-l. round-bottomed flask are placed 750 g. (8.1 moles) of aniline and 1 kg. Please login to view your saved searches. The crystal structure of benzanilide has been determined from Weissenberg photographs using Cu Kα radiations and refined to an R value of 0.075 for 766 independent reflections. Home; About us; Membership & professional community; Campaigning & outreach; Journals, books & databases; Teaching & learning; News & events; Locations & contacts; Home; About us; Web APIs; Help ; Sign in; ChemSpider Search and share chemistry. Structural modifications of benzanilide derivatives, effective potassium channel openers. Natural modulators of large-conductance calcium-activated potassium channels.

Product Classification | IX. Their vasorelaxing effects, induced through the activation of BK channels, were also evaluated. Chem. weißer Feststoff mit schwach aromatischem Geruch[1]. The Crystal and Molecular Structure of μ3-Hydroxo-tri-μ-(2-chlorobenzoato)dizinc(II) Dihydrate, The Crystal and Molecular Structure of Benzanilide. Jump to main content Jump to site nav.

In Table 1 an overview of different dihedral angles for both conformers is given. About Us | Eur J Med Chem. 74(2) , 484-97, (2009). NLM N -Phenylbenzoesäureamid. Tokarčík M, Gowda BT, Kožíšek J, Sowmya BP, Fuess H. Acta Crystallogr Sect E Struct Rep Online. c1ccc(cc1)C(=O)Nc2ccccc2 Nardi A, Calderone V, Chericoni S, Morelli I. Planta Med.

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From a structural point of view, these benzanilides belong to a general class of BK-activators, showing a common pharmacophoric model, consisting of two aryl groups linked through an appropriate “spacer” and the almost obligatory presence of a phenolic hydroxyl. 2009. Benzanilide | C13H11NO | CID 7168 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. CopyCopied, Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, Predicted data is generated using the US Environmental Protection Agency’s EPISuite™, Click to predict properties on the Chemicalize site, For medical information relating to Covid-19, please consult the. Benzanilide is the organic compound with the formula C 6 H 5 C(O)NHC 6 H 5. : ) could be produced through the following synthetic route. New amido derivatives as potential BKCa potassium channel activators. References This page was last edited on 11 June 2020, at 14:57 (UTC). The crystals are monoclinic, space group C2/c, Z =4, with a =24.34 (4), b =5.325 (3), c =8.012 (8) … (8.2 moles) of benzoic acid. 2003 Oct;69(10):885-92. doi: 10.1055/s-2003-45095. 2008 Apr;43(4):792-9. doi: 10.1016/j.ejmech.2007.06.005. Heterocyclic analogs of benzanilide derivatives as potassium channel activators. Benzanilide is the organic compound with the formula C 6 H 5 C(O)NHC 6 H 5. This site needs JavaScript to work properly.